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CCR6 Protein (Fc Tag)

CCR6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092813
  • Target See all CCR6 Proteins
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CCR6 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human CCR6 with C-terminal human Fc tag
    Specificity
    CCR6 (Met1-Leu47) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CCR6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    Alternative Name
    CCR6 (CCR6 Products)
    Synonyms
    BN-1 Protein, C-C CKR-6 Protein, CC-CKR-6 Protein, CCR-6 Protein, CD196 Protein, CKR-L3 Protein, CKRL3 Protein, CMKBR6 Protein, DCR2 Protein, DRY6 Protein, GPR29 Protein, GPRCY4 Protein, STRL22 Protein, Cmkbr6 Protein, KY411 Protein, C-C motif chemokine receptor 6 Protein, chemokine (C-C motif) receptor 6 Protein, CCR6 Protein, Ccr6 Protein
    Background
    Synonymes: BN-1
    Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 31.6 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P51684
    Pathways
    cAMP Metabolic Process
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