GPR77 Protein (AA 1-38) (Fc Tag)
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- Target See all GPR77 Proteins
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-38
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GPR77 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human GPR77(1-38) with C-terminal human Fc tag
- Specificity
- GPR77 (Met1-Pro38) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product GPR77 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- Alternative Name
- GPR77 (GPR77 Products)
- Synonyms
- GPR77 Protein, C5L2 Protein, GPF77 Protein, E030029A11Rik Protein, Gpr77 Protein, complement component 5a receptor 2 Protein, C5AR2 Protein, C5ar2 Protein
- Background
- This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
- Molecular Weight
- predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of GPR77(1-38)-hFc is 35-55 kDa due to glycosylation.
- UniProt
- Q9P296
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