GPR77 Protein
GPR77
Origin: Human
Host: HEK-293 Cells
Synthetic
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- Target See all GPR77 Proteins
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human C5AR2 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GPR77 Protein
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G Protein-Coupled Receptor 77 (GPR77) (AA 1-337) protein (GST tag)
GPR77 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR77 (G Protein-Coupled Receptor 77 (GPR77))
- Alternative Name
- C5AR2 (GPR77 Products)
- Synonyms
- GPR77 Protein, C5L2 Protein, GPF77 Protein, E030029A11Rik Protein, Gpr77 Protein, complement component 5a receptor 2 Protein, C5AR2 Protein, C5ar2 Protein
- Background
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C5L2, GPF77, GPR77
Description: This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] - Molecular Weight
- The human full length C5AR2 protein has a MW of 36.1 kDa
- UniProt
- Q9P296
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