CLEC5A Protein (His tag)
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- Target See all CLEC5A Proteins
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC5A protein is labelled with His tag.
- Purpose
- Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
- Sequence
- Pro 28 - Lys 188
- Characteristics
- Human CLEC5A, His Tag (CLA-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 28 - Lys 188 (Accession # Q9NY25-1).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Grade
- MALS verified
- Top Product
- Discover our top product CLEC5A Protein
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C-Type Lectin Domain Family 5, Member A (CLEC5A) (AA 26-188) protein (Fc Tag)
CLEC5A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 5, Member A (CLEC5A) (AA 26-190) protein (Fc Tag)CLEC5A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
C-Type Lectin Domain Family 5, Member A (CLEC5A) (AA 1-188) protein (GST tag)CLEC5A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
C-Type Lectin Domain Family 5, Member A (CLEC5A) protein (His tag)CLEC5A Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Application Notes
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 20.3 kDa. The protein migrates as 60-66 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Alternative Name
- CLEC5A / MDL-1 (CLEC5A Products)
- Synonyms
- CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
- Background
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Synonyms: CLEC5A,CLECSF5,superfamilymember 5,C-type lectin domain family 5, member A,MDL1,MDL-1,DAP12-associating lectin 1,
Description: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. - Molecular Weight
- 20.3 kDa
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