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CLEC5A Protein (His tag)

CLEC5A Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7321165
  • Target See all CLEC5A Proteins
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 1
    Rat
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CLEC5A protein is labelled with His tag.
    Purpose
    Recombinant Rat CLEC5A/MDL1/MDL-1 Protein (His Tag)
    Sequence
    Val30-Lys190
    Characteristics
    A DNA sequence encoding the rat CLEC5A (F7GAV1) (Val30-Lys190) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product CLEC5A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    Alternative Name
    CLEC5A/MDL1/MDL-1 (CLEC5A Products)
    Synonyms
    CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
    Background

    Background: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

    Synonym: CLEC5A

    Molecular Weight
    20.6 kDa
    UniProt
    F7GAV1
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