CLEC4C Protein (His tag)
MALS verified
CLEC4C
Origin: Human
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- Target See all CLEC4C products
- CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC4C protein is labelled with His tag.
- Purpose
- Human CLEC4C / BDCA2 Protein, His Tag (MALS verified)
- Sequence
- Asn 45 - Ile 213
- Characteristics
- Human CLEC4C, His Tag (CLC-H5245) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Grade
- MALS verified
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C-Type Lectin Domain Family 4, Member C (CLEC4C) (AA 45-213) protein (His-SUMO Tag)
CLEC4C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 33-40 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
- Alternative Name
- CLEC4C / BDCA2 (CLEC4C Products)
- Synonyms
- BDCA2 Protein, CD303 Protein, CLECSF11 Protein, CLECSF7 Protein, DLEC Protein, HECL Protein, PRO34150 Protein, Clec4c Protein, C-type lectin domain family 4 member C Protein, CLEC4C Protein, LOC100733227 Protein
- Background
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Synonyms: DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL,
Description: CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. - Molecular Weight
- 26.6 kDa
- NCBI Accession
- NP_569708
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