SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (C.37 - Lambda) (His tag)
-
- Target See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) Proteins
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- Protein Type
- Recombinant
- Protein Characteristics
- C.37 - Lambda
-
Origin
- SARS Coronavirus-2 (SARS-CoV-2), SARS-CoV-2 Lambda
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.
- Purpose
- SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag
- Sequence
- Met 1 - Ala 419
- Specificity
- SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C)
- Characteristics
- SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). Mutations P13L, R203K, G204R, G214C were identified in the SARS-CoV-2 Lambda variant (Pango lineage: C.37).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 N Protein
-
-
- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, 0.5 M Arginine, pH 7.3
- Storage
- -20 °C
- Storage Comment
- -20°C
-
- Target
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- Alternative Name
- SARS-CoV-2 Nucleocapsid protein (SARS-CoV-2 N Products)
- Synonyms
- nucleocapsid phosphoprotein Protein, N Protein
- Background
-
Synonyms: Nucleocapsid protein,NP,Protein N,
Description: Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool. - Molecular Weight
- 47.4 kDa
-