ADAM9 Protein (His tag)
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- Target See all ADAM9 Proteins
- ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ADAM9 protein is labelled with His tag.
- Purpose
- Recombinant Mouse ADAM9 Protein (His Tag)
- Sequence
- Met 1-Asp 697
- Characteristics
- A DNA sequence encoding the mouse ADAM9 (Q61072) extracellular domain (Met 1-Asp 697) was expressed with a C-terminal polyhistidine tag.
- Purity
- > 87 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product ADAM9 Protein
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ADAM Metallopeptidase Domain 9 (ADAM9) (AA 29-697) protein (His tag)
ADAM9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
ADAM Metallopeptidase Domain 9 (ADAM9) (AA 36-135) protein (GST tag)ADAM9 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))
- Alternative Name
- ADAM9 (ADAM9 Products)
- Synonyms
- CORD9 Protein, MCMP Protein, MDC9 Protein, Mltng Protein, AU020942 Protein, mKIAA0021 Protein, adam9-A Protein, cord9 Protein, mcmp Protein, mltng Protein, Adam9 Protein, zgc:101824 Protein, ADAM9 Protein, ADAM metallopeptidase domain 9 Protein, a disintegrin and metallopeptidase domain 9 (meltrin gamma) Protein, ADAM metallopeptidase domain 9 L homeolog Protein, ADAM9 Protein, Adam9 Protein, adam9.L Protein, adam9 Protein
- Background
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Background: ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential therapeutic target in tumors where it is highly expressed. ADAM9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases involved in protein ectodomain shedding and cell-cell and cell-matrix interactions. ADAM-9 adhesive domain plays a role in regulating the motility of cells by interaction with beta1 integrins and modulates MMP synthesis.
Synonym: AU020942,MDC9,mKIAA0021,Mltng
- Molecular Weight
- 74.9 kDa
- UniProt
- Q61072
- Pathways
- Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome
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