CD147 Protein (His tag)

Catalog No. ABIN7321285

Product Details

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Protein Type: Recombinant

Origin: Rat

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CD147 protein is labelled with His tag.

Purpose: Recombinant Rat CD147/BSG/Basigin Protein (His Tag)

Sequence: Pro52-Thr324

Characteristics: A DNA sequence encoding the Rat BSG (P26453-1) (Pro52-Thr324) was expressed with a polyhistidine tag at the N-terminus.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: CD147/BSG/Basigin (BSG Products)

Synonyms: EMMPRIN Protein, RPE7 Protein, 5F7 Protein, CD147 Protein, M6 Protein, OK Protein, TCSF Protein, AI115436 Protein, AI325119 Protein, HT-7 Protein, 5A11 Protein, CE9 Protein, HT7 Protein, Ox47R Protein, basignin Protein, wu:fb26a05 Protein, wu:fo98e12 Protein, bsg Protein, prso03 Protein, basigin (Ok blood group) Protein, basigin Protein, basigin (Ok blood group) S homeolog Protein, BSG Protein, Bsg Protein, bsg Protein, bsg.S Protein

Background:

Background: BSG,also named as 5F7,Basigin,EMMPRIN,TCSF and CD147,plays pivotal roles in spermatogenesis,embryo implantation,neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1,SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA,inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix,plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.

Synonym: 5A11 antigen,5F7,BASI,Basigin (Ok blood group),Basigin,Blood brain barrier HT7 antigen,Bsg,CD 147,CD147,CD147 antigen,Collagenase stimulatory factor,EMMPRIN,Extracellular matrix metalloproteinase inducer,Leukocyte activation antigen M6,M 6,M6,M6 leukocyte activation antigen,Neurothelin,OK,OK blood group,OK blood group antigen,TCSF,Tumor cell derived collagenase stimulatory factor,Tumor cell-derived collagenase stimulatory factor

Molecular Weight: 30.27 kDa

Pathways: S100 Proteins