CD147 Protein (AA 22-205) (His tag)
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- Target See all CD147 (BSG) Proteins
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-205
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD147 protein is labelled with His tag.
- Purpose
- Human EMMPRIN/CD147 Protein
- Sequence
- Ala22-His205
- Characteristics
- Recombinant Human EMMPRIN/CD147 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-His205.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human EMMPRIN, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-EMMPRIN Antibody, hFc Tag with the EC50 of 9.8ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
- Alternative Name
- EMMPRIN (BSG Products)
- Synonyms
- EMMPRIN Protein, RPE7 Protein, 5F7 Protein, CD147 Protein, M6 Protein, OK Protein, TCSF Protein, AI115436 Protein, AI325119 Protein, HT-7 Protein, 5A11 Protein, CE9 Protein, HT7 Protein, Ox47R Protein, basignin Protein, wu:fb26a05 Protein, wu:fo98e12 Protein, bsg Protein, prso03 Protein, basigin (Ok blood group) Protein, basigin Protein, basigin (Ok blood group) S homeolog Protein, BSG Protein, Bsg Protein, bsg Protein, bsg.S Protein
- Background
- CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
- Molecular Weight
- 21.2 kDa. Due to glycosylation, the protein migrates to 28-40 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_940991
- Pathways
- S100 Proteins
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