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CD83 Protein (CD83) (AA 1-133) (His tag)

CD83 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320187
  • Target See all CD83 Proteins
    CD83
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-133
    Origin
    • 13
    • 7
    • 2
    • 1
    Mouse
    Source
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD83 protein is labelled with His tag.
    Purpose
    Recombinant Mouse CD83/HB15 Protein (aa 1-133, His Tag)
    Sequence
    Met 1-Arg 133
    Characteristics
    A DNA sequence encoding the extracellular domain of mouse CD83 (O88324) (Met 1-Arg 133) was expressed, with a C-terminal polyhistidine tag.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product CD83 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD83
    Alternative Name
    CD83/HB15 (CD83 Products)
    Synonyms
    BL11 Protein, HB15 Protein, CD83 molecule Protein, CD83 antigen Protein, Cd83 Protein, CD83 Protein
    Background

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.

    Synonym: CD83 Antigen, hCD83, B-Cell Activation Protein, Cell Surface Protein HB15, CD83

    Molecular Weight
    13.6 kDa
    UniProt
    O88324
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