COL4a3 Protein (Fc Tag)
-
- Target See all COL4a3 (COL4A3) Proteins
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- Protein Type
- Recombinant
-
Origin
- Rat
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This COL4a3 protein is labelled with Fc Tag.
- Purpose
- Recombinant Rat COL4A3 Protein (Fc Tag)
- Sequence
- Gly1426-His1670
- Characteristics
- A DNA sequence encoding the rat COL4A3 (NP_001129231) (Gly1426-His1670) was expressed with Fc region of human IgG1 at the N-terminus.
- Purity
- > 85 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
-
Collagen, Type IV, alpha 3 (COL4A3) (AA 1446-1667), (partial) protein (His tag)
COL4A3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- Alternative Name
- COL4A3 (COL4A3 Products)
- Synonyms
- zTumstatin Protein, [a]3(IV) Protein, alpha3(IV) Protein, collagen type IV alpha 3 chain Protein, collagen, type IV, alpha 3 Protein, COL4A3 Protein, col4a3 Protein, Col4a3 Protein
- Background
-
Background: COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a head-to-head conformation and each gene pair shares a common promoter.
Synonym: COL4A3
- Molecular Weight
- 55.2 kDa
- NCBI Accession
- NP_001129231
- Pathways
- Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity
-
