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FGF17 Protein (His tag)

FGF17 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318480
  • Target See all FGF17 Proteins
    FGF17 (Fibroblast Growth Factor 17 (FGF17))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 7
    • 4
    • 1
    • 1
    Human
    Source
    • 9
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This FGF17 protein is labelled with His tag.
    Purpose
    Recombinant Human FGF-17 Protein (His Tag)(Active)
    Sequence
    Thr 23-Thr 216
    Characteristics
    Recombinant Human Fibroblast Growth Factor 17 is produced by our Mammalian expression system and the target gene encoding Thr23-Thr216 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 2.1 ug/ml.
    Top Product
    Discover our top product FGF17 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    FGF17 (Fibroblast Growth Factor 17 (FGF17))
    Alternative Name
    FGF-17 (FGF17 Products)
    Synonyms
    FGF17 Protein, FGF-13 Protein, HH20 Protein, fgf17b Protein, zgc:101759 Protein, fibroblast growth factor 17 Protein, FGF17 Protein, Fgf17 Protein, fgf17 Protein
    Background

    Background: Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition, FGF17 stimulates the proliferation and activation of cells that express FGF receptors.

    Synonym: Fibroblast Growth Factor 17, FGF-17, FGF17

    Molecular Weight
    22.6 kDa
    UniProt
    O60258
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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