FGF17 Protein (His tag)
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- Target See all FGF17 Proteins
- FGF17 (Fibroblast Growth Factor 17 (FGF17))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FGF17 protein is labelled with His tag.
- Purpose
- Recombinant Mouse FGF-17 Protein (His Tag)(Active)
- Sequence
- Thr23-Thr216
- Characteristics
- Recombinant Mouse Fibroblast Growth Factor 17 is produced by our E.coli expression system and the target gene encoding Thr23-Thr216 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells. The ED50 for this effect is 1.26 ug/ml, in the presence of 10 μg/mL heparin.
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Fibroblast Growth Factor 17 (FGF17) (AA 23-216) protein (His tag)
FGF17 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 17 (FGF17) (AA 100-199) protein (GST tag)FGF17 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 17 (FGF17) (AA 23-216) protein (His tag)Crystallography grade FGF17 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl,EDTA,DTT, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- FGF17 (Fibroblast Growth Factor 17 (FGF17))
- Alternative Name
- FGF-17 (FGF17 Products)
- Synonyms
- FGF17 Protein, FGF-13 Protein, HH20 Protein, fgf17b Protein, zgc:101759 Protein, fibroblast growth factor 17 Protein, FGF17 Protein, Fgf17 Protein, fgf17 Protein
- Background
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Background: FGF-17 is a member of the fibroblast growth factor (FGF) family. FGFs share 30 70 % amino acid (aa) identity in a conserved, approximately 120 amino acid core domain. FGFs play multiple roles in biological functions, including angiogenesis, mitogenesis, cell differentiation and wound repair. FGF17 plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also expressed in hindgut, parts of the developing skeleton, tail bud, major arteries, and heart. In many of these areas, it is expressed along with FGF-8, but slightly later. It is required for normal brain development.
Synonym: Fibroblast growth factor 17, FGF-17,fgf17
- Molecular Weight
- 23.7 kDa
- UniProt
- P63075
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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