HAVCR1 Protein (His tag)

Catalog No. ABIN7320829

Product Details

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purification tag / Conjugate: This HAVCR1 protein is labelled with His tag.

Purpose: Recombinant Mouse TIM1/HAVCR1 Protein (His Tag)

Sequence: Tyr22-Thr212

Characteristics: Recombinant Mouse TIM-1 is produced by our Mammalian expression system and the target gene encoding Tyr22-Thr212 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Alternative Name: TIM1/HAVCR1 (HAVCR1 Products)

Synonyms: HAVCR Protein, HAVCR-1 Protein, KIM-1 Protein, KIM1 Protein, TIM Protein, TIM-1 Protein, TIM1 Protein, TIMD-1 Protein, TIMD1 Protein, Kim1 Protein, HAVCR1 Protein, LOC100226241 Protein, AI503787 Protein, Tim1 Protein, Timd1 Protein, hepatitis A virus cellular receptor 1 Protein, hepatitis A virus cellular receptor 1 homolog Protein, HAVCR1 Protein, Havcr1 Protein, LOC100226241 Protein

Target Type: Virus

Background:

Background: TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.

Synonym: Hepatitis A virus cellular receptor 1 homolog, HAVcr-1, Kidney injury molecule 1, KIM-1, T cell membrane protein 1, TIM-1,Timd1,AI503787

Molecular Weight: 21.8 kDa

UniProt: Q5QNS5