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HAVCR1 Protein (AA 21-295) (His tag)

HAVCR1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275734
  • Target See all HAVCR1 Proteins
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-295
    Origin
    • 16
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 12
    • 9
    • 3
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This HAVCR1 protein is labelled with His tag.
    Purpose
    Human TIM-1/HAVCR1 Protein
    Sequence
    Ser21-Gly295
    Characteristics
    Recombinant Human TIM-1/HAVCR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Gly295.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    Alternative Name
    TIM-1 (HAVCR1 Products)
    Synonyms
    HAVCR Protein, HAVCR-1 Protein, KIM-1 Protein, KIM1 Protein, TIM Protein, TIM-1 Protein, TIM1 Protein, TIMD-1 Protein, TIMD1 Protein, Kim1 Protein, HAVCR1 Protein, LOC100226241 Protein, AI503787 Protein, Tim1 Protein, Timd1 Protein, hepatitis A virus cellular receptor 1 Protein, hepatitis A virus cellular receptor 1 homolog Protein, HAVCR1 Protein, Havcr1 Protein, LOC100226241 Protein
    Background
    Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation.
    Molecular Weight
    30.58 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.
    UniProt
    Q96D42
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