INPP5A Protein (His tag)

Catalog No. ABIN7319135

Product Details

Target: INPP5A (Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This INPP5A protein is labelled with His tag.

Purpose: Recombinant Human INPP5A Protein (His Tag)

Sequence: Met 1-Val410

Characteristics: Recombinant Human Type I Inositol-polyphosphate Phosphatase is produced by our Mammalian expression system and the target gene encoding Met1-Val410 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: INPP5A (Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A))

Alternative Name: INPP5A (INPP5A Products)

Synonyms: 5PTASE Protein, inositol polyphosphate-5-phosphatase A Protein, INPP5A Protein

Background:

Background: Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Synonym: Type I inositol 1,4,5-trisphosphate 5-phosphatase, INPP5A

Molecular Weight: 48.5 kDa

UniProt: Q14642