LILRA3 Protein (Fc Tag)
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- Target See all LILRA3 Proteins
- LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRA3 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human ILT6/LILRA3 Protein (Fc Tag)
- Sequence
- Met 1-Glu439
- Characteristics
- A DNA sequence encoding the human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 80 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LILRA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
- Alternative Name
- ILT6/LILRA3 (LILRA3 Products)
- Synonyms
- CD85E Protein, HM31 Protein, HM43 Protein, ILT-6 Protein, ILT6 Protein, LIR-4 Protein, LIR4 Protein, e3 Protein, leukocyte immunoglobulin like receptor A3 Protein, LILRA3 Protein
- Background
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Background: ILT6, also known as LILRA3, belongs to the ILT family. In human, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Synonym: Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31,CD85e,HM31,HM43,ILT6,LIR-4,LIR4
- Molecular Weight
- 72 kDa
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