LILRA3 Protein (AA 24-439) (His-Avi Tag)
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- Target See all LILRA3 Proteins
- LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-439
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRA3 protein is labelled with His-Avi Tag.
- Purpose
- Human LILRA3/CD85e Protein
- Sequence
- Gly24-Glu439
- Characteristics
- Recombinant Human LILRA3/CD85e Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly24-Glu439.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product LILRA3 Protein
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Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) (AA 24-439) protein (His-Avi Tag,Biotin)
LILRA3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) (AA 340-439) protein (GST tag)LILRA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) (AA 1-439) protein (GST tag)LILRA3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3) (AA 24-439) protein (His tag)Crystallography grade LILRA3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4).Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
- Alternative Name
- LILRA3 (LILRA3 Products)
- Synonyms
- CD85E Protein, HM31 Protein, HM43 Protein, ILT-6 Protein, ILT6 Protein, LIR-4 Protein, LIR4 Protein, e3 Protein, leukocyte immunoglobulin like receptor A3 Protein, LILRA3 Protein
- Background
- Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31, is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
- Molecular Weight
- 47.9 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8N6C8
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