LILRA3 Protein (His tag)
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- Target See all LILRA3 Proteins
- LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRA3 protein is labelled with His tag.
- Purpose
- Recombinant Human LILRA3/CD85e Protein
- Sequence
- GPLPKPTLWA EPGSVITQGS PVTLRCQGSL ETQEYHLYRE KKTALWITRI PQELVKKGQF PILSITWEHA GRYCCIYGSH TAGLSESSDP LELVVTGAYS KPTLSALPSP VVTSGGNVTI QCDSQVAFDG FILCKEGEDE HPQCLNSHSH ARGSSRAIFS VGPVSPSRRW SYRCYGYDSR APYVWSLPSD LLGLLVPGVS KKPSLSVQPG PVVAPGEKLT FQCGSDAGYD RFVLYKEWGR DFLQRPGRQP QAGLSQANFT LGPVSRSYGG QYTCSGAYNL SSEWSAPSDP LDILITGQIR ARPFLSVRPG PTVASGENVT LLCQSQGGMH TFLLTKEGAA DSPLRLKSKR QSHKYQAEFP MSPVTSAHAG TYRCYGSLSS NPYLLTHPSD PLELVVSGAA ETLSPPQNKS DSKAGE
- Specificity
- Gly24-Glu439
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <1EU/μg
- Top Product
- Discover our top product LILRA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
- Alternative Name
- LILRA3/CD85e (LILRA3 Products)
- Synonyms
- CD85E Protein, HM31 Protein, HM43 Protein, ILT-6 Protein, ILT6 Protein, LIR-4 Protein, LIR4 Protein, e3 Protein, leukocyte immunoglobulin like receptor A3 Protein, LILRA3 Protein
- Background
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Description: LILRA3, also known as ILT6, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Name: LILRA3,ILT6,LIR4,CD85e,LILRA3
- Gene ID
- 11026
- UniProt
- Q8N6C8
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