MECP2 Protein (His tag)
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- Target See all MECP2 Proteins
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This MECP2 protein is labelled with His tag.
- Purpose
- Recombinant Human MECP2 Protein (His Tag)
- Sequence
- Met 1-Ser486
- Characteristics
- Recombinant Human Methyl-CpG-binding protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Ser486 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MECP2 Protein
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Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (GST tag)
MECP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Methyl CpG Binding Protein 2 (MECP2) (AA 329-486) protein (His tag)MECP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) protein (GST tag)MECP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (Strep Tag)Crystallography grade MECP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Methyl CpG Binding Protein 2 (MECP2) (AA 1-484) protein (Strep Tag)Crystallography grade MECP2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
- Alternative Name
- MECP2 (MECP2 Products)
- Synonyms
- AUTSX3 Protein, MRX16 Protein, MRX79 Protein, MRXS13 Protein, MRXSL Protein, PPMX Protein, RS Protein, RTS Protein, RTT Protein, 1500041B07Rik Protein, BB130002 Protein, D630021H01Rik Protein, Mbd5 Protein, WBP10 Protein, wu:fk96a04 Protein, zgc:111857 Protein, methyl-CpG binding protein 2 Protein, methyl CpG binding protein 2 Protein, methyl-CpG binding protein 2 S homeolog Protein, MECP2 Protein, Mecp2 Protein, mecp2 Protein, mecp2.S Protein
- Background
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Background: The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may also be necessary for the function of other types of brain cells.
Synonym: Methyl-CpG-binding protein 2,MECP2,MeCp-2 protein
- Molecular Weight
- 53.5 kDa
- UniProt
- P51608
- Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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