MECP2 Protein (AA 1-177) (His tag)
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- Target See all MECP2 Proteins
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-177
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MECP2 protein is labelled with His tag.
- Sequence
- Met1-Lys177
- Characteristics
- A DNA sequence encoding theHuman MeCP2 protein (P51608) (Met1-Lys177) was expressed with a N-His .
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MECP2 Protein
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Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (GST tag)
MECP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Methyl CpG Binding Protein 2 (MECP2) (AA 329-486) protein (His tag)MECP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) protein (GST tag)MECP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (Strep Tag)Crystallography grade MECP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Methyl CpG Binding Protein 2 (MECP2) (AA 1-484) protein (Strep Tag)Crystallography grade MECP2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
- Alternative Name
- MeCP2 (MECP2 Products)
- Synonyms
- AUTSX3 Protein, MRX16 Protein, MRX79 Protein, MRXS13 Protein, MRXSL Protein, PPMX Protein, RS Protein, RTS Protein, RTT Protein, 1500041B07Rik Protein, BB130002 Protein, D630021H01Rik Protein, Mbd5 Protein, WBP10 Protein, wu:fk96a04 Protein, zgc:111857 Protein, methyl-CpG binding protein 2 Protein, methyl CpG binding protein 2 Protein, methyl-CpG binding protein 2 S homeolog Protein, MECP2 Protein, Mecp2 Protein, mecp2 Protein, mecp2.S Protein
- Background
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Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Synonym: MeCp-2 protein
- Molecular Weight
- 19 kDa
- UniProt
- P51608
- Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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