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SERPINB3 Protein (His tag)

SERPINB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319019
  • Target See all SERPINB3 Proteins
    SERPINB3 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3))
    Protein Type
    Recombinant
    Origin
    • 10
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SERPINB3 protein is labelled with His tag.
    Purpose
    Recombinant Human SerpinB3/SCCA1 Protein (E.coli, His Tag)
    Sequence
    Met 1-Pro390
    Characteristics
    Recombinant Human Serine Protease Inhibitor-clade B3 is produced by our E.coli expression system and the target gene encoding Met1-Pro390 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product SERPINB3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SERPINB3 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3))
    Alternative Name
    SerpinB3/SCCA1 (SERPINB3 Products)
    Synonyms
    HsT1196 Protein, SCC Protein, SCCA-1 Protein, SCCA-PD Protein, SCCA1 Protein, T4-A Protein, LEUPIN Protein, PI11 Protein, SCCA-2 Protein, SCCA2 Protein, serpin family B member 3 Protein, serpin family B member 4 Protein, serpin B3 Protein, Somatic cell count Protein, SERPINB3 Protein, SERPINB4 Protein, Serpinb3 Protein, LOC483954 Protein, SCC Protein
    Background

    Background: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

    Synonym: Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1,serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3, serpin peptidase inhibitor, clade B (ovalbumin), member 3, Squamous cell carcinoma antigen 1,T4-A,SCCA1,HsT1196,SCC,SCCA-1,SCCA-PD

    Molecular Weight
    46.0 kDa
    UniProt
    P29508
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