SMPDL3A Protein (His tag)
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- Target See all SMPDL3A Proteins
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SMPDL3A protein is labelled with His tag.
- Purpose
- Recombinant Human SMPDL3A Protein (His Tag)
- Sequence
- Leu23-Tyr453
- Characteristics
- Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a is produced by our Mammalian expression system and the target gene encoding Leu23-Tyr453 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SMPDL3A Protein
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Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 1-453) protein (GST tag)
SMPDL3A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) protein (His tag)SMPDL3A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- Alternative Name
- SMPDL3A (SMPDL3A Products)
- Synonyms
- ASM3A Protein, ASML3a Protein, yR36GH4.1 Protein, 0610010C24Rik Protein, AI529588 Protein, ASML3 Protein, ASML3A Protein, sphingomyelin phosphodiesterase acid like 3A Protein, sphingomyelin phosphodiesterase, acid-like 3A Protein, SMPDL3A Protein, Smpdl3a Protein
- Background
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Background: Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A ) is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases.
Synonym: Acid Sphingomyelinase-Like Phosphodiesterase 3a, ASM-Like Phosphodiesterase 3a,SMPDL3A,ASML3A
- Molecular Weight
- 49.9 kDa
- UniProt
- Q92484
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