TPP1 Protein (His tag)
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- Target See all TPP1 Proteins
- TPP1 (Tripeptidyl Peptidase I (TPP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This TPP1 protein is labelled with His tag.
- Purpose
- Recombinant Human TPP1/CLN2 Protein (His Tag)
- Sequence
- Ser20-Pro563
- Characteristics
- Recombinant Human TPP1 is produced by our Mammalian expression system and the target gene encoding Ser20-Pro563 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TPP1 Protein
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Tripeptidyl Peptidase I (TPP1) (AA 195-304) protein (GST tag)
TPP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tripeptidyl Peptidase I (TPP1) (AA 1-563) protein (GST tag)TPP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tripeptidyl Peptidase I (TPP1) (AA 196-563) protein (His tag)Crystallography grade TPP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Tripeptidyl Peptidase I (TPP1) (AA 195-562) protein (His tag)Crystallography grade TPP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TPP1 (Tripeptidyl Peptidase I (TPP1))
- Alternative Name
- TPP1/CLN2 (TPP1 Products)
- Synonyms
- cln2 Protein, fa01b09 Protein, im:7149243 Protein, wu:fa01b09 Protein, CLN2 Protein, LPIC Protein, TPP-1 Protein, TPP-I Protein, Cln2 Protein, tripeptidyl peptidase I Protein, tripeptidyl-peptidase 1 Protein, tripeptidyl peptidase 1 Protein, tpp1 Protein, NAEGRDRAFT_78259 Protein, MCYG_00184 Protein, MGYG_05881 Protein, MGYG_00757 Protein, TPP1 Protein, Tpp1 Protein
- Background
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Background: Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).
Synonym: Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, TPP1, CLN2,GIG1,LPIC,SCAR7,TPP-1
- Molecular Weight
- 60.35 kDa
- UniProt
- O14773
- Pathways
- Cell Division Cycle, ER-Nucleus Signaling
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