TNFRSF18 Protein (Fc Tag)
Quick Overview for TNFRSF18 Protein (Fc Tag) (ABIN7321198)
Target
See all TNFRSF18 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This TNFRSF18 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rat GITR/TNFRSF18 Protein (Fc Tag)
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Sequence
- Met1-Lys121
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Characteristics
- A DNA sequence encoding the rat TNFRSF18 (Q5M835) (Met1-Lys121) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
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Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) (Active) protein (His tag)
TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 20-156) (Active) protein (His tag)TNFRSF18 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) (Active) protein (Biotin,His-Avi Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) protein (His tag,mFc Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) protein (His tag,Fc Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 22-153) (Active) protein (His tag)TNFRSF18 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 1-241) protein (GST tag)TNFRSF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) protein (GST tag)TNFRSF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (Active) protein (His tag,Fc Tag)TNFRSF18 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 22-153) protein (Fc Tag)TNFRSF18 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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Alternative Name
- GITR/TNFRSF18
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Background
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Background: GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Immune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: TNFRSF18
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Molecular Weight
- 37.7 kDa
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UniProt
- Q5M835
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Pathways
- Cancer Immune Checkpoints
Target
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