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CD52 Protein (CD52) (AA 25-36) (mFc Tag)

CD52 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274198
  • Target See all CD52 Proteins
    CD52
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-36
    Origin
    • 10
    • 2
    Human
    Source
    • 8
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD52 protein is labelled with mFc Tag.
    Purpose
    Human CD52 Protein
    Sequence
    Gly25-Ser36
    Characteristics
    Recombinant Human CD52 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Gly25-Ser36.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 15.9μM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CD52
    Alternative Name
    CD52 (CD52 Products)
    Synonyms
    CD52 Protein, AI463198 Protein, B7 Protein, B7-Ag Protein, CAMPATH-1 Protein, CLS1 Protein, MB7 Protein, CDW52 Protein, CE5 Protein, CD52 molecule Protein, CD52 antigen Protein, CD52 Protein, Cd52 Protein
    Background
    CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. Mature human CD52 is a 12 amino acid peptide that is tethered to the cell surface with a GPI linkage.CD52 may play a role in carrying and orienting carbohydrate, as well as having a more specific role.
    Molecular Weight
    27.6 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
    UniProt
    P31358
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