CD52 Protein (CD52) (AA 25-36) (mFc Tag)
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- Target See all CD52 Proteins
- CD52
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-36
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD52 protein is labelled with mFc Tag.
- Purpose
- Human CD52 Protein
- Sequence
- Gly25-Ser36
- Characteristics
- Recombinant Human CD52 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Gly25-Ser36.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 15.9μM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD52
- Alternative Name
- CD52 (CD52 Products)
- Synonyms
- CD52 Protein, AI463198 Protein, B7 Protein, B7-Ag Protein, CAMPATH-1 Protein, CLS1 Protein, MB7 Protein, CDW52 Protein, CE5 Protein, CD52 molecule Protein, CD52 antigen Protein, CD52 Protein, Cd52 Protein
- Background
- CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. Mature human CD52 is a 12 amino acid peptide that is tethered to the cell surface with a GPI linkage.CD52 may play a role in carrying and orienting carbohydrate, as well as having a more specific role.
- Molecular Weight
- 27.6 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
- UniProt
- P31358
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