CADM3 Protein (AA 25-329) (His tag)
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- Target See all CADM3 Proteins
- CADM3 (Cell Adhesion Molecule 3 (CADM3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-329
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CADM3 protein is labelled with His tag.
- Purpose
- Human CADM3 Protein
- Sequence
- Asn25-Tyr329
- Characteristics
- Recombinant Human CADM3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn25-Tyr329.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CADM3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CADM3 (Cell Adhesion Molecule 3 (CADM3))
- Alternative Name
- CADM3 (CADM3 Products)
- Synonyms
- BIgR Protein, IGSF4B Protein, NECL1 Protein, Necl-1 Protein, TSLL1 Protein, synCAM3 Protein, Igsf4b Protein, Necl1 Protein, SynCAM3 Protein, Tsll1 Protein, necl1 Protein, cell adhesion molecule 3 Protein, cell adhesion molecule 3 S homeolog Protein, CADM3 Protein, Cadm3 Protein, cadm3.S Protein
- Background
- Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compared to DRG neurons.
- Molecular Weight
- 34.6 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.
- Pathways
- Cell-Cell Junction Organization
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