CLEC7A Protein (AA 66-201) (Fc Tag)
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- Target See all CLEC7A Proteins
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 66-201
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC7A protein is labelled with Fc Tag.
- Purpose
- Human CLEC7A Protein
- Sequence
- Thr66-Met201
- Characteristics
- Recombinant Human CLEC7A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Thr66-Met201.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC7A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- Alternative Name
- CLEC7A (CLEC7A Products)
- Synonyms
- CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein
- Background
- Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders.
- Molecular Weight
- 41.79 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
- Pathways
- Activation of Innate immune Response
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