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CLEC7A Protein (AA 71-244) (Fc Tag)

CLEC7A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274366
  • Target See all CLEC7A Proteins
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 71-244
    Origin
    • 7
    • 5
    • 1
    • 1
    Mouse
    Source
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CLEC7A protein is labelled with Fc Tag.
    Purpose
    Mouse CLEC7A Protein
    Sequence
    Gly71-Leu244
    Characteristics
    Recombinant Mouse CLEC7A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gly71-Leu244.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Alternative Name
    CLEC7A (CLEC7A Products)
    Synonyms
    CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein
    Background
    Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders.
    Molecular Weight
    46.08 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
    UniProt
    Q6QLQ4
    Pathways
    Activation of Innate immune Response
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