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Desmoglein 2 Protein (DSG2) (AA 55-618) (His tag)

DSG2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7274502
  • Target See all Desmoglein 2 (DSG2) Proteins
    Desmoglein 2 (DSG2)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 55-618
    Origin
    • 5
    • 3
    Mouse
    Source
    • 6
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Desmoglein 2 protein is labelled with His tag.
    Purpose
    Mouse DSG-2/Desmoglein-2 Protein
    Sequence
    Ala55-Ala618
    Characteristics
    Recombinant Mouse DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala55-Ala618.
    Purity
    > 95 % as determined by Tris-Bis PAGE
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product DSG2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Desmoglein 2 (DSG2)
    Alternative Name
    DSG-2 (DSG2 Products)
    Synonyms
    DSG2 Protein, dsc Protein, dsga Protein, si:dkeyp-51f12.6 Protein, wu:fj23f02 Protein, ARVC10 Protein, ARVD10 Protein, CDHF5 Protein, CMD1BB Protein, HDGC Protein, AA408168 Protein, D18Ertd293e Protein, desmoglein 2 Protein, desmoglein 2, tandem duplicate 1 Protein, DSG2 Protein, dsg2.1 Protein, dsg2 Protein, Dsg2 Protein
    Background
    Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
    Molecular Weight
    63.7 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
    UniProt
    O55111
    Pathways
    Cell-Cell Junction Organization
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