FOLR2 Protein (AA 17-228) (His tag)
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- Target See all FOLR2 Proteins
- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-228
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FOLR2 protein is labelled with His tag.
- Purpose
- Human FOLR2 Protein
- Sequence
- Thr17-Met228
- Characteristics
- Recombinant Human FOLR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Met228.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human FOLR2, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-FOLR2 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA. See testing image for detail.
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Folate Receptor 2 (Fetal) (FOLR2) (AA 9-187) protein (His tag)
FOLR2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 2 (Fetal) (FOLR2) (AA 21-227) protein (His tag)FOLR2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 2 (Fetal) (FOLR2) (AA 1-255) protein (GST tag)FOLR2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Folate Receptor 2 (Fetal) (FOLR2) (AA 36-128) protein (GST tag)FOLR2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Folate Receptor 2 (Fetal) (FOLR2) (AA 34-245) protein (His tag)FOLR2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
- Alternative Name
- FOLR2 (FOLR2 Products)
- Synonyms
- FOLR2 Protein, BETA-HFR Protein, FBP Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FBP2 Protein, Folbp-2 Protein, Folbp2 Protein, folate receptor 1 Protein, folate receptor beta Protein, folate receptor 2 (fetal) Protein, FOLR1 Protein, FOLR2 Protein, Folr2 Protein
- Background
- FOLR1 and FOLR2 are equipped with cellular glycosylphosphatidylinositol (GPI) anchors. FOLR1 is secreted from epithelia with or without a micelle-encapsulated GPI-anchor into milk and other body fluids/secretions, e.g. semen where its interaction with spermatozoa indicates a role in male fertility. FOLR1 and FOLR2 serve as serum biomarkers of various diseases. FOLR3 possesses no GPI-anchor and originates from secretory granules of neutrophil granulocytes, its concentration in serum correlates to the FOLR3 content in leukocytes and rises with increased leukocyte counts (infection, malignancy and pregnancy).
- Molecular Weight
- 25.5 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.
- UniProt
- P14207
- Pathways
- Dicarboxylic Acid Transport
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