Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL3RA Protein (AA 18-302) (His tag)

IL3RA Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274938
  • Target See all IL3RA Proteins
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-302
    Origin
    • 18
    • 4
    • 1
    • 1
    Cynomolgus
    Source
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL3RA protein is labelled with His tag.
    Purpose
    Cynomolgus IL-3 R alpha/CD123 Protein
    Sequence
    Arg18-Arg302
    Characteristics
    Recombinant Cynomolgus IL-3 R alpha/CD123 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg18-Arg302.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 48.13 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL3RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Alternative Name
    IL-3 R alpha (IL3RA Products)
    Synonyms
    CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
    Background
    Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
    Molecular Weight
    33.9 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    Pathways
    JAK-STAT Signaling
You are here:
Support