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IL17F Protein (His-Avi Tag,Biotin)

IL17F Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Catalog No. ABIN7275004
  • Target See all IL17F Proteins
    IL17F (Interleukin 17F (IL17F))
    Protein Type
    Recombinant
    Origin
    • 15
    • 10
    • 7
    • 2
    • 1
    Human
    Source
    • 14
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL17F protein is labelled with His-Avi Tag,Biotin.
    Sequence
    Arg31-Gln163
    Purity
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-17 R alpha, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-17F, His Tag with the EC50 of 1.1ug/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL17F (Interleukin 17F (IL17F))
    Alternative Name
    IL-17F (IL17F Products)
    Synonyms
    CANDF6 Protein, IL-17F Protein, ML-1 Protein, ML1 Protein, C87042 Protein, IL17F Protein, interleukin 17F Protein, IL17F Protein, Il17f Protein
    Background
    Cytokine ML-1, IL17F, IL-17F, IL24, IL-24, CANDF6, IL-17F, ML1,The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus.IL-17F is ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover.
    Molecular Weight
    17.5 /14.9 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.
    UniProt
    Q96PD4
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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