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IL23R Protein (AA 24-354) (His tag)

IL23R Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275011
  • Target See all IL23R Proteins
    IL23R (Interleukin 23 Receptor (IL23R))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-354
    Origin
    • 17
    • 7
    • 2
    • 2
    Dog
    Source
    • 11
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL23R protein is labelled with His tag.
    Purpose
    Canine IL-23R Protein
    Sequence
    Gly24-Asp354
    Characteristics
    Recombinant Canine IL-23R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-Asp354.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product IL23R Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL23R (Interleukin 23 Receptor (IL23R))
    Alternative Name
    IL-23R (IL23R Products)
    Synonyms
    IL-23R Protein, IL23R Protein, il-23r Protein, interleukin 23 receptor Protein, IL23R Protein, il23r Protein, Il23r Protein
    Background
    Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).This receptor associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade.
    Molecular Weight
    39.31 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A8I3PXL0
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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