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Layilin Protein (LAYN) (AA 22-235) (His tag)

LAYN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275132
  • Target See all Layilin (LAYN) Proteins
    Layilin (LAYN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-235
    Origin
    • 9
    • 3
    • 3
    • 1
    Human
    Source
    • 6
    • 4
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Layilin protein is labelled with His tag.
    Purpose
    Human LAYN Protein
    Sequence
    Ala22-Leu235
    Characteristics
    Recombinant Human LAYN Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-Leu235.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Layilin (LAYN)
    Alternative Name
    LAYN (LAYN Products)
    Synonyms
    LAYN Protein, si:dkey-27p23.2 Protein, E030012M19Rik Protein, Gm511 Protein, RGD1564444 Protein, layilin Protein, layilin a Protein, LAYN Protein, layna Protein, Layn Protein
    Background
    Layilin (LAYN) is a critical gene that regulates T cell function. LAYN is correlated with prognosis and immune infiltrating levels of, including those of CD8 T cells, CD4 T cells, macrophages, neutrophils, and DCs in multiple cancers, especially in colon and gastric cancer patients. In addition, LAYN expression potentially contributes to regulation of tumor-associated macrophages (TAMs), DCs, T cell exhaustion and Tregs in colon and gastric cancer.
    Molecular Weight
    25.4 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Tris-Bis PAGE result.
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