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MMP8 Protein (AA 21-465) (His tag)

MMP8 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275273
  • Target See all MMP8 Proteins
    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-465
    Origin
    • 8
    • 4
    • 3
    • 2
    • 1
    Mouse
    Source
    • 9
    • 6
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MMP8 protein is labelled with His tag.
    Purpose
    Mouse MMP-8 Protein (pro form)
    Sequence
    Phe21-Ser465
    Characteristics
    Recombinant Mouse MMP-8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe21-Ser465.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product MMP8 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 50 mM Tris, 10 mM CaCl2, 150 mM NaCl ( pH 7.5).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
    Alternative Name
    MMP-8 (MMP8 Products)
    Synonyms
    MMP8 Protein, BB138268 Protein, CLG1 Protein, HNC Protein, MMP-8 Protein, PMNL-CL Protein, matrix metallopeptidase 8 Protein, neutrophil collagenase Protein, MMP8 Protein, Mmp8 Protein, LOC100339790 Protein
    Background
    Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.
    Molecular Weight
    51.9 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
    UniProt
    O70138
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