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PVRL4 Protein (His tag)

PVRL4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Catalog No. ABIN7275304
  • Target See all PVRL4 Proteins
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    Protein Type
    Recombinant
    Origin
    • 24
    • 8
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    Source
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This PVRL4 protein is labelled with His tag.
    Sequence
    Gly32-Val351
    Purity
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus Nectin-4, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Nectin-4 Antibody, hFc Tag with the EC50 of 5.9ng/ml determined by ELISA. See testing image for detail.
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    Discover our top product PVRL4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Storage
    4 °C,-80 °C
    Storage Comment
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    Alternative Name
    Nectin-4 (PVRL4 Products)
    Synonyms
    PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein
    Background
    EDSS1, LNIR, Nectin4, PRR4, NECTIN4, PVRL4,Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus.
    Molecular Weight
    35.9 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    XP_005541277
    Pathways
    Cell-Cell Junction Organization
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