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SARS-CoV-2 Spike S2 Protein (BA.1 - Omicron) (Biotin,His-Avi Tag)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron Host: HEK-293 Cells Recombinant 95,00 %
Catalog No. ABIN7447846
  • Target See all SARS-CoV-2 Spike S2 Proteins
    SARS-CoV-2 Spike S2
    Protein Type
    Recombinant
    Protein Characteristics
    BA.1 - Omicron
    Origin
    • 14
    • 2
    • 1
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
    Source
    • 12
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SARS-CoV-2 Spike S2 protein is labelled with Biotin,His-Avi Tag.
    Purpose
    Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.1/Omicron)
    Sequence
    Ser 686 - Pro 1213
    Characteristics
    Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.1/Omicron) is expressed from human 293 cells (HEK293). It contains AA Ser Ser 686 - Pro 1213 (Accession # QHD43416.1 (N764K, D796Y, N856K, Q954H, N969K, L981F, F817P, A892P, A899P, A942P, K986P, V987P). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.1, GISAID clade: GRA, Nextstrain clade: 21K). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to prevent the formation of aggregates in the course of protein production.
    Purity
    95,00 %
    Endotoxin Level
    1.0 EU per μg
    Top Product
    Discover our top product SARS-CoV-2 Spike S2 Protein
  • Comment

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 61.7 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    SARS-CoV-2 Spike S2
    Alternative Name
    SARS-CoV-2 Spike S2 protein (SARS-CoV-2 Spike S2 Products)
    Synonyms
    E2 Protein, Surface Glycoprotein Protein, S Protein
    Target Type
    Viral Protein
    Background
    Synonyms:Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    Molecular Weight
    61.7 kDa
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