HCST Protein (Fc Tag)
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- Target See all HCST Proteins
- HCST (Hematopoietic Cell Signal Transducer (HCST))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HCST protein is labelled with Fc Tag.
- Purpose
- Recombinant human DAP10 protein with C-terminal human Fc tag
- Specificity
- DAP10 (Gln19-Pro48) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Hematopoietic Cell Signal Transducer (HCST) (AA 20-48) (Active) protein (hIgG-His-tag)
HCST Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS Active
Hematopoietic Cell Signal Transducer (HCST) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HCST Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- HCST (Hematopoietic Cell Signal Transducer (HCST))
- Alternative Name
- DAP10 (HCST Products)
- Synonyms
- DAP10 Protein, KAP10 Protein, PIK3AP Protein, Dap10 Protein, HCST Protein, dap10 Protein, dap10-A Protein, hcst Protein, hcsta Protein, kap10 Protein, pik3ap Protein, hematopoietic cell signal transducer Protein, hematopoietic cell signal transducer L homeolog Protein, HCST Protein, Hcst Protein, hcst Protein, hcst.L Protein
- Background
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HCST, KAP10, PIK3AP
Description: This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] - Molecular Weight
- predicted molecular mass of 29.1 kDa after removal of the signal peptide. The apparent molecular mass of DAP10-hFc is 25-55 kDa due to glycosylation.
- UniProt
- Q9UBK5
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