Midkine Protein (Fc Tag)

Catalog No. ABIN7490871

Product Details

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Midkine protein is labelled with Fc Tag.

Purpose: Recombinant human MDK protein with C-terminal human Fc tag

Specificity: MDK (Val21-Asp143) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Alternative Name: MDK (MDK Products)

Synonyms: ARAP Protein, MK Protein, NEGF2 Protein, Mek Protein, MK-B Protein, PTF-alpha-1 Protein, mdk Protein, midkine Protein, negf2 Protein, RIHB Protein, cb518 Protein, fb79b05 Protein, fj33b02 Protein, fj48a12 Protein, mdk2 Protein, plei2 Protein, wu:fb79b05 Protein, wu:fj33b02 Protein, wu:fj48a12 Protein, MK-A Protein, PTF-alpha-2 Protein, X-PTF-alpha1 Protein, XMK Protein, mdk-a Protein, mdk-b Protein, midkine Protein, midkine L homeolog Protein, midkine (neurite growth-promoting factor 2) Protein, midkine b Protein, midkine S homeolog Protein, MDK Protein, Mdk Protein, mdk.L Protein, mdkb Protein, mdk.S Protein

Background: Midkine,MK,ARAP,Midgestation and kidney protein,Neurite outgrowth-promoting factor 2,Neurite outgrowth-promoting protein
Description: This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Molecular Weight: predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of MDK-hFc is 35-55 kDa due to glycosylation.

UniProt: P21741

Pathways: RTK Signaling, M Phase, Skeletal Muscle Fiber Development