RNF43 Protein (mFc Tag)
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- Target See all RNF43 Proteins
- RNF43 (Ring Finger Protein 43 (RNF43))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RNF43 protein is labelled with mFc Tag.
- Purpose
- Recombinant human RNF43 protein with C-terminal mouse Fc tag
- Specificity
- RNF43 (Glu43-Tyr197) mFc (Pro99-Lys330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product RNF43 Protein
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Ring Finger Protein 43 (RNF43) (AA 44-197) (Active) protein (Fc Tag)
RNF43 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Ring Finger Protein 43 (RNF43) (AA 24-197) protein (His tag)Crystallography grade RNF43 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Ring Finger Protein 43 (RNF43) (AA 24-197) protein (His tag)Crystallography grade RNF43 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Ring Finger Protein 43 (RNF43) (AA 219-783) protein (His tag)Crystallography grade RNF43 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Ring Finger Protein 43 (RNF43) (AA 219-784) protein (His tag)Crystallography grade RNF43 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Ring Finger Protein 43 (RNF43) (AA 24-783) protein (rho-1D4 tag)Crystallography grade RNF43 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Ring Finger Protein 43 (RNF43) (AA 24-784) protein (rho-1D4 tag)Crystallography grade RNF43 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- RNF43 (Ring Finger Protein 43 (RNF43))
- Alternative Name
- RNF43 (RNF43 Products)
- Synonyms
- RNF124 Protein, URCC Protein, 4732452J19Rik Protein, RGD1305204 Protein, ring finger protein 43 Protein, RNF43 Protein, Rnf43 Protein
- Background
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RNF124, SSPCS, URCC
Description: The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] - Molecular Weight
- predicted molecular mass of 39.4 kDa after removal of the signal peptide. The apparent molecular mass of RNF43-mFc is 40-70 kDa due to glycosylation.
- UniProt
- Q68DV7
- Pathways
- WNT Signaling
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