HCRTR1 Protein (Fc Tag)

Catalog No. ABIN7491309

Product Details

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HCRTR1 protein is labelled with Fc Tag.

Purpose: Recombinant Human HCRTR1 Protein with C-terminal human Fc tag

Specificity: HCRTR1 (Met1-Glu46) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Alternative Name: HCRTR1 (HCRTR1 Products)

Synonyms: OX1R Protein, Ox1r Protein, Hctr1 Protein, HCRTR1 Protein, hypocretin receptor 1 Protein, hypocretin (orexin) receptor 1 Protein, HCRTR1 Protein, Hcrtr1 Protein

Background: ORXR1, OX1R, OXR1
Description: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]

Molecular Weight: predicted molecular mass of 31.5 kDa after removal of the signal peptide. The apparent molecular mass of HCRTR1-hFc is 35-55 kDa due to glycosylation.

UniProt: O43613

Pathways: Feeding Behaviour