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HCRTR1 Protein

HCRTR1 Origin: Human Host: HEK-293 Cells Synthetic
Catalog No. ABIN7491681
  • Target See all HCRTR1 Proteins
    HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))
    Protein Type
    Synthetic
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purpose
    Human HCRTR1 full length protein-synthetic nanodisc
    Characteristics
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product HCRTR1 Protein
  • Application Notes
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    Comment

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))
    Alternative Name
    HCRTR1 (HCRTR1 Products)
    Synonyms
    OX1R Protein, Ox1r Protein, Hctr1 Protein, HCRTR1 Protein, hypocretin receptor 1 Protein, hypocretin (orexin) receptor 1 Protein, HCRTR1 Protein, Hcrtr1 Protein
    Background
    ORXR1, OX1R, OXR1
    Description: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]
    Molecular Weight
    The human full length HCRTR1 protein has a MW of 47.5 kDa
    UniProt
    O43613
    Pathways
    Feeding Behaviour
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