HCRTR1 Protein
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- Target See all HCRTR1 Proteins
- HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human HCRTR1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product HCRTR1 Protein
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))
- Alternative Name
- HCRTR1 (HCRTR1 Products)
- Synonyms
- OX1R Protein, Ox1r Protein, Hctr1 Protein, HCRTR1 Protein, hypocretin receptor 1 Protein, hypocretin (orexin) receptor 1 Protein, HCRTR1 Protein, Hcrtr1 Protein
- Background
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ORXR1, OX1R, OXR1
Description: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009] - Molecular Weight
- The human full length HCRTR1 protein has a MW of 47.5 kDa
- UniProt
- O43613
- Pathways
- Feeding Behaviour
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