CD133 Protein
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- Target See all CD133 (PROM1) products
- CD133 (PROM1) (Prominin 1 (PROM1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human PROM1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
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Prominin 1 (PROM1) protein (Fc Tag)
PROM1 Origin: Rat Host: HEK-293 Cells Recombinant (79.2+14.5) % as determined by SDS-PAGE
Prominin 1 (PROM1) protein (His tag)PROM1 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD133 (PROM1) (Prominin 1 (PROM1))
- Alternative Name
- PROM1 (PROM1 Products)
- Synonyms
- Prom Protein, AC133 Protein, CD133 Protein, Prom-1 Protein, Proml1 Protein, 4932416E19Rik Protein, CORD12 Protein, MCDR2 Protein, PROML1 Protein, RP41 Protein, STGD4 Protein, prominin 1 Protein, Prom1 Protein, PROM1 Protein
- Background
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AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Description: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] - Molecular Weight
- The human full length PROM1 protein has a MW of 97 kDa
- UniProt
- O43490
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