CD133 Protein-VLP
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- Target See all CD133 (PROM1) products
- CD133 (PROM1) (Prominin 1 (PROM1))
- Protein Type
- VLP
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CD133 Full Length Protein (VLP)
- Sequence
- Gly 20 - His 865
- Characteristics
- Human CD133 Full Length-VLP is expressed from human 293 cells (HEK293). It contains AA Gly 20 - His 865 (Accession # O43490-1).
- Endotoxin Level
- 1.0 EU per μg
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C
- Storage Comment
- -70°C
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- Target
- CD133 (PROM1) (Prominin 1 (PROM1))
- Alternative Name
- CD133 (PROM1 Products)
- Synonyms
- Prom Protein, AC133 Protein, CD133 Protein, Prom-1 Protein, Proml1 Protein, 4932416E19Rik Protein, CORD12 Protein, MCDR2 Protein, PROML1 Protein, RP41 Protein, STGD4 Protein, prominin 1 Protein, Prom1 Protein, PROM1 Protein
- Background
- Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
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