Ret Proto-Oncogene Protein (RET) (AA 29-635) (His tag)

Catalog No. ABIN7504518

Product Details

Target: Ret Proto-Oncogene (RET)

Protein Type: Recombinant

Protein Characteristics: AA 29-635

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Ret Proto-Oncogene protein is labelled with His tag.

Purpose: Human RET Protein

Sequence: Leu29-Arg635

Characteristics: Recombinant Human RET Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu29-Arg635.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Ret Proto-Oncogene (RET)

Alternative Name: RET (RET Products)

Synonyms: c-ret Protein, cret Protein, etID315074.13 Protein, ret1 Protein, wu:fd13h01 Protein, X-ret Protein, ret-A Protein, xret Protein, RET Protein, MTC1 Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, RET9 Protein, c-Ret Protein, ret proto-oncogene receptor tyrosine kinase Protein, ret proto-oncogene S homeolog Protein, ret proto-oncogene Protein, ret Protein, ret.S Protein, RET Protein, Ret Protein

Background: RET is a proto-oncogene encoding a receptor tyrosine kinase. RET regulates key aspects of cellular proliferation, differentiation and survival. The activation of RET via gene fusions or point mutations is closely related to lung, thyroid and other cancers.

Molecular Weight: 68.87 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation