alpha Actinin 4 Protein (AA 1-300) (His tag)
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- Target See all alpha Actinin 4 (ACTN4) Proteins
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-300
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This alpha Actinin 4 protein is labelled with His tag.
- Sequence
- Met1-Lys300
- Characteristics
- A DNA sequence encoding theHuman ACTN4 protein (O43707-1) (Met1-Lys300) was expressed with a N-His.
- Purity
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ACTN4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Alternative Name
- ACTN4 (ACTN4 Products)
- Synonyms
- fsgs Protein, fsgs1 Protein, C77391 Protein, ACTININ-4 Protein, FSGS Protein, FSGS1 Protein, wu:fb53f05 Protein, zgc:63508 Protein, actinin alpha 4 Protein, actinin, alpha 4 Protein, actinin alpha 4 S homeolog Protein, actn4 Protein, ACTN4 Protein, Actn4 Protein, actn4.S Protein
- Background
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Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.
Synonym: Non-muscle alpha-actinin 4
- Molecular Weight
- 34 kDa
- Pathways
- Proton Transport
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