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alpha Actinin 4 Protein (AA 1-300) (His tag)

ACTN4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505019
  • Target See all alpha Actinin 4 (ACTN4) Proteins
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-300
    Origin
    • 8
    • 2
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This alpha Actinin 4 protein is labelled with His tag.
    Sequence
    Met1-Lys300
    Characteristics
    A DNA sequence encoding theHuman ACTN4 protein (O43707-1) (Met1-Lys300) was expressed with a N-His.
    Purity
    >90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ACTN4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Alternative Name
    ACTN4 (ACTN4 Products)
    Synonyms
    fsgs Protein, fsgs1 Protein, C77391 Protein, ACTININ-4 Protein, FSGS Protein, FSGS1 Protein, wu:fb53f05 Protein, zgc:63508 Protein, actinin alpha 4 Protein, actinin, alpha 4 Protein, actinin alpha 4 S homeolog Protein, actn4 Protein, ACTN4 Protein, Actn4 Protein, actn4.S Protein
    Background

    Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.

    Synonym: Non-muscle alpha-actinin 4

    Molecular Weight
    34 kDa
    Pathways
    Proton Transport
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