RAD51 Protein (AA 2-339) (His tag)
Quick Overview for RAD51 Protein (AA 2-339) (His tag) (ABIN7505246)
Target
See all RAD51 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 2-339
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Purification tag / Conjugate
- This RAD51 protein is labelled with His tag.
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Sequence
- Ala 2-Asp 339
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Characteristics
- A DNA sequence encoding the Human Rad51 protein (Q06609) (Ala 2-Asp 339) was expressed with a N-His.
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DNA Repair Protein Homolog 1 (RAD51) (AA 1-242) protein (GST tag)
RAD51 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
DNA Repair Protein Homolog 1 (RAD51) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RAD51 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
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Alternative Name
- Rad51
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Background
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Abbreviation: Rad51
Target Synonym: DNA repair protein RAD51 homolog 1,RAD51, HsRAD51,hRAD51
Background: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
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Molecular Weight
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Calculated MW: 37.07 kDa
Observed MW: 38 kDa
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UniProt
- Q06609
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Pathways
- DNA Damage Repair
Target
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