Patched 1 Protein (PTCH1) (AA 122-436) (His tag)

Catalog No. ABIN7505336

Product Details

Target: Patched 1 (PTCH1)

Protein Type: Recombinant

Protein Characteristics: AA 122-436

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Patched 1 protein is labelled with His tag.

Sequence: Glu 122-Asp 436

Characteristics: A DNA sequence encoding the Human PTCH1 protein (Q13635) (Glu 122-Asp 436) was expressed with a N-His tag.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Patched 1 (PTCH1)

Alternative Name: PTCH1 (PTCH1 Products)

Synonyms: BCNS Protein, HPE7 Protein, NBCCS Protein, PTC Protein, PTC1 Protein, PTCH Protein, PTCH11 Protein, lep Protein, ptc1 Protein, ptc2 Protein, Ptch Protein, Ptch2 Protein, Ptc-1 Protein, XPtc1 Protein, patched Protein, patched1 Protein, A230106A15Rik Protein, Ptc Protein, Ptc1 Protein, mes Protein, patched 1 Protein, patched 1 L homeolog Protein, Protein patched homolog 1 Protein, PTCH1 Protein, ptch1 Protein, Ptch1 Protein, ptch1.L Protein, ptc-1 Protein

Background:

Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this prot

Synonym: Protein patched homolog 1,PTCH1,PTC, PTC1

Molecular Weight: 34.54 kDa

UniProt: Q13635

Pathways: Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation